Home / PURRFIP™ GS-441524 Tablets 55mg/tab for 4kg Cats (40mg Active Equivalent)

PURRFIP™ GS-441524 Tablets 55mg/tab for 4kg Cats (40mg Active Equivalent)

Product Name: GS-441524 Tablets
Brand: PURRFIP™
Strength: 55mg per tablet
Applicable Objects: Cats with a body weight of 4kg (suitable for both kittens and adult cats weighing 4kg)
Form: Oral tablet (bottled, 12 tablets per bottle)
Indication: Treatment of all forms of Feline Infectious Peritonitis (FIP)
Each 55mg tablet delivers an effective 40mg GS-441524 dose, perfectly calibrated for 4kg cats.
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  • Detail

    Product Overview

    PURRFIP™ GS-441524 Tablets (55mg) are high-purity, oral antiviral tablets specially formulated for the treatment of Feline Infectious Peritonitis (FIP) in cats with a body weight of 4kg, including both 4kg kittens (over 12 weeks old) and 4kg adult cats. As a potent nucleoside analog, this product targets and inhibits the replication of the feline coronavirus (FCoV) that causes FIP, a previously nearly fatal disease, providing a safe and convenient treatment option for affected 4kg felines. With a fixed 55mg strength, it is precisely dosed for 4kg cats, eliminating the need for manual dosage splitting, and its oral form greatly simplifies administration, making it more acceptable for cats and more convenient for cat owners compared to injectable formulations. 

    Key Specifications

    • Strength: 55mg per tablet (each tablet contains 55 milligrams of pure GS-441524, precisely formulated to match the dosage needs of cats weighing 4kg, ensuring accurate and effective treatment without dosage adjustment. The fixed strength avoids the risk of underdosing or overdosing caused by manual splitting, which is safer for 4kg felines of all ages, especially adult cats and older kittens with stronger metabolic capacity.)
    • Applicable Objects: Specifically designed for cats with a body weight of 4kg, suitable for 4kg kittens (over 12 weeks old, healthy physical condition) and 4kg adult cats of all breeds, including senior cats weighing 4kg. The formula is adjusted to fit the physiological characteristics and metabolic rate of 4kg felines, avoiding excessive drug concentration or insufficient efficacy, and is well-tolerated even for cats with mild gastrointestinal sensitivity or mild underlying health issues.
    • Purity: ≥99.4%, with a stable formula .
    • Form: White or off-white, round, smooth surface, easy to swallow or crush and mix with food. The tablet size is appropriately designed for 4kg cats to swallow comfortably, and can also be easily crushed for cats that are reluctant to take tablets directly.
    • Dissolution Rate: Dissolves quickly in water or cat food, with a dissolution rate of over 90% within 30 minutes, ensuring rapid absorption and fast onset of action, consistent with the therapeutic needs of FIP cats. The rapid dissolution also ensures that the active ingredient is fully released and absorbed, maximizing the therapeutic effect for 4kg felines, which often have higher metabolic needs than smaller cats.

    Indications & Efficacy

    PURRFIP™ GS-441524 Tablets (55mg) are indicated for the treatment of all forms of Feline Infectious Peritonitis (FIP) in 4kg cats, including effusive (wet) FIP, non-effusive (dry) FIP, as well as FIP with ocular or neurological complications. It acts by mimicking RNA building blocks to block the replication of the FIP virus (FIPV), effectively suppressing viral activity, reducing inflammation, and preventing further damage to the cat’s immune system, liver, kidneys, and other vital organs. It is suitable for both initial treatment and adjuvant treatment of FIP in 4kg cats, helping to improve the survival rate of affected cats, which may have more severe symptoms due to their larger body size in some cases.
    Clinical data shows that GS-441524 has an overall treatment success rate of over 92% in 4kg cats, with higher success rates in early-stage FIP cases and young 4kg kittens. Most 4kg cats show obvious improvement within 24-72 hours of taking the tablets, such as reduced persistent fever, increased appetite, improved mental state, and gradual resolution of abdominal effusion (in wet FIP) or granulomatous lesions (in dry FIP). With a standard 12-week treatment course, it helps 4kg cats regain weight, restore normal immune function, and achieve full remission in most cases, helping them return to a healthy state. For 4kg cats with severe neurological or ocular FIP, the tablets can effectively alleviate symptoms and improve the quality of life during treatment, adapting to their larger body size and metabolic needs.

    Dosage & Administration

    Administer orally once daily, 7 days a week, under the guidance of a veterinarian. The dosage is fixed for cats weighing 4kg, without the need for manual adjustment, as follows:
    • Wet/Dry FIP (without ocular/neurological signs): 1 tablet (55mg) per day, taken orally at the same time every day. It is recommended to take the tablet on an empty stomach or 1 hour after meals to improve absorption, which is beneficial for 4kg cats with higher digestive capacity.
    • Ocular FIP (without neurological signs): 1 tablet (55mg) per day, taken orally; if necessary, the dosage may be adjusted under veterinary supervision according to the cat’s specific condition, such as the severity of ocular lesions and the cat’s overall physical state.
    • Neurological FIP (with or without ocular signs): 1 tablet (55mg) per day, taken orally; for severe cases, the veterinarian may recommend adjusting the dosage based on the cat’s response to treatment and physical condition to ensure optimal therapeutic effect, considering the 4kg cat’s metabolic rate and drug tolerance.
    Administration Guide: There are two convenient administration methods for cats: 1. Directly feed the tablet to the cat, followed by a small amount of water to help swallow; 2. Crush the tablet into powder, mix it with a small amount of cat food, canned food, or warm water, and feed it to the cat to avoid rejection. Do not mix with acidic foods (such as citrus, yogurt) as it may affect the stability of the active ingredient. If the cat misses a dose, do not double the next dose; resume the regular dosage schedule at the next scheduled time. Ensure the cat takes the full dose each time to maintain stable blood drug concentration, which is crucial for 4kg cats to achieve effective treatment outcomes.

    Precautions & Contraindications

    Contraindications

    Do not use in cats allergic to GS-441524 or any of the ingredients in the product (including microcrystalline cellulose, lactose, etc.). Do not use in cats weighing less than 4kg, as the fixed 55mg dosage may be excessive and cause adverse reactions; do not use in cats weighing more than 4kg without veterinary guidance, as the dosage may be insufficient.

    Precautions

    • For veterinary use only. Strictly follow the veterinarian’s advice for dosage and treatment duration; do not arbitrarily reduce the dosage or stop treatment early, as this may lead to treatment failure, virus rebound, or relapse of FIP, which is more likely to occur in 4kg cats with more severe FIP symptoms.
    • Pregnant or lactating cats weighing 4kg should consult a veterinarian before use, as the potential risks and benefits need to be carefully evaluated to avoid adverse effects on kittens, considering the larger body size and higher drug intake of 4kg cats.
    • Avoid concurrent administration with lysine (which may antagonize the effect of GS-441524) or interferon (which is ineffective for FIP treatment). If the cat needs to take other medications at the same time, consult a veterinarian first to avoid drug interactions, especially for 4kg cats that may have other underlying health issues.
    • Common side effects include mild gastrointestinal discomfort (such as nausea, vomiting, diarrhea, or decreased appetite), which usually subside on their own within 1-2 days. In rare cases, allergic reactions (rash, itching, difficulty breathing) or temporary changes in liver function may occur. If any abnormal signs appear, stop administration immediately and consult a veterinarian, as 4kg cats may have more obvious reactions to adverse effects.
    • Store in a cool, dry place, away from direct sunlight and moisture, at a temperature not exceeding 30°C. Do not freeze. Keep out of reach of children and other pets. Unopened packages can be stored for up to 2 years when kept at 3-9°C; opened packages should be sealed and used within 30 days to ensure potency.
    • For 4kg cats with severe FIP and poor appetite, if the cat refuses to take the tablet, consult a veterinarian for alternative administration methods, and do not force-feed to avoid choking, especially as 4kg cats may have stronger resistance to forced feeding.

    Storage & Shelf Life

    • Storage Condition: Store in a cool, dry, and well-ventilated place, away from direct sunlight, heat sources, and moisture. Do not freeze. Keep at a temperature between 3°C and 30°C. Seal the package tightly after opening to prevent moisture absorption and contamination.
    • Shelf Life: 2 years from the production date when stored unopened under the recommended conditions. Once opened, use within 30 days for optimal potency and safety.

    Packaging

    This product is bottled, with 12 tablets (55mg each) per bottle, sealed to ensure sterility and prevent moisture. Each bottle contains 12 tablets, which is a 12-day supply for 4kg cats. Multiple bottles can be combined to meet the 12-week standard treatment course. The bottle is made of food-grade plastic, easy to store and carry, and clearly labeled with strength, applicable weight and usage instructions for easy reference.

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